Monkey IL-4 ELISA kit - 5-plate

SKU
CT143A
All-inclusive ELISA kit with reagents and plates (480 determinations).
Species reactivity: rhesus macaque, cynomolgus monkey, pig-tailed macaque, barbary macaque and baboon.
Format
5-plate
Price
€ 530
Reactivity
Monkey
Category
ELISA
Analyte
IL-4
Range
0.5-32 pg/ml
Description
Our sandwich ELISA kits are developed for the determination of cytokines in culture supernatant, serum and plasma. Each kit includes all reagents required to perform up to 480 ELISA determinations: coating and detection antibodies, standards, streptavidin-HRP conjugate, TMB substrate, stop solution, cytokine stabilization buffer, BSA stock solution, ELISA plates and adhesive plate covers.
Description
Interleukin-4 (IL-4) is a key cytokine that plays a central role in regulating the immune system. It is primarily produced by T helper 2 (Th2) cells, but can also be secreted by mast cells, and eosinophils and basophils. IL-4 is involved in several critical immune processes, including IgE class switching in B cell, Th2 cell differentiation, allergic inflammation and defense against parasites.
Alternative names
IL-4, Interleukin 4, Interleukin-4, IL4, BCGF-1, BGF1, BSF-1, BSF1, IL4E12
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References

Authors, et al. Title Journal Year Volume Pages
Weidong Zhang Schistosoma mansoni antigen Sm-p80: prophylactic efficacy using TLR4 agonist vaccine adjuvant glucopyranosyl lipid A-Alum in murine and non-human primate models J Investig Med 2018 66 1124-1132
Christopher Coe Immune senescence in old and very old rhesus monkeys: reduced antibody response to influenza vaccination Age (Dordr) 2012 34 1169-77
Matthias Tenbusch Immunogenicity of DNA vaccines encoding simian immunodeficiency virus antigen targeted to dendritic cells in rhesus macaques PLoS One 2012 7 e39038
Dianne McFarlane Age-associated alteration in innate immune response in captive baboons J Gerontol A Biol Sci Med Sci 2011 66 1309-17
Gul Ahmad Preclinical prophylactic efficacy testing of Sm-p80-based vaccine in a nonhuman primate model of Schistosoma mansoni infection and immunoglobulin G and E responses to Sm-p80 in human serum samples from an area where schistosomiasis is endemic J Infect Dis 2011 204 1437-49
Y Qiu Comparison of immunological responses of plague vaccines F1+rV270 and EV76 in Chinese-origin rhesus macaque, Macaca mulatta Scand J Immunol 2010 72 425-33
Weidong Zhang Sm-p80-based DNA vaccine provides baboons with levels of protection against Schistosoma mansoni infection comparable to those achieved by the irradiated cercarial vaccine J Infect Dis 2010 201 1105-12
Christiane Stahl-Hennig Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques PLoS Pathog 2009 5 e1000373
Gunther Hartmann CpG oligonucleotides induce strong humoral but only weak CD4+ T cell responses to protein antigens in rhesus macaques in vivo Vaccine 2005 23 3310-7
Koen Van Rompay Tenofovir primes rhesus macaque cells in vitro for enhanced interleukin-12 secretion Antiviral Res 2004 63 133-8