IL-21 is a pro-inflammatory cytokine and is produced by several T cells, including CD4+, T follicular helper and T helper 17 cells. Overproduction of IL-21 occurs in many inflammatory diseases such as rheumatoid arthritis, SLE and organ transplantation.
The level of IL-21 in supernatant can be determined by ELISA. The IL-21 capacity of T cells or the frequency of IL-21 producing cells can be determined by ELISPOT assay. U-CyTech's Human IL-21 ELISA or ELISPOT assay allows you to measure the important IL-21 cytokine.
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