Human IL-23 ELISA kit - 5-plate

SKU
CT517A
All-inclusive ELISA kit with reagents and plates (480 determinations).
Format
5-plate
Price
€ 530
Reactivity
Human
Category
ELISA
Analyte
IL-23
Range
4-256 pg/ml
Description
Our sandwich ELISA kits are developed for the determination of cytokines in culture supernatant, serum and plasma. Each kit includes all reagents required to perform up to 480 ELISA determinations: coating and detection antibodies, standards, streptavidin-HRP conjugate, TMB substrate, stop solution, cytokine stabilization buffer, BSA stock solution, ELISA plates and adhesive plate covers.
Description
Interleukin-23 (IL-23) is a pro-inflammatory cytokine that plays a critical role in immune regulation. IL-23 is a heterodimer composed of two subunits: IL12p40 and IL-23p19. It is primarily secreted by antigen-presenting cells, including dendritic cell, macrophages and monocytes.
IL-23 is responsible for the expansion and maintenance of T helper 17 (Th17) cells, a subset of CD4 T cells involved in host defense and inflammatory responses.
Alternative names
IL-23, Interleukine-23, IL23, Interleukin 23, IL23A, IL-23p19, P19,
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References

Authors, et al. Title Journal Year Volume Pages
Lynn Mes IgA2 immune complexes selectively promote inflammation by human CD103+ dendritic cells Front Immunol 2023 14 1116435
Florianne Hafkamp Vitamin D3 Priming of Dendritic Cells Shifts Human Neutrophil-Dependent Th17 Cell Development to Regulatory T Cells Front Immunol 2022 13 872665
Chiara Geyer C-Reactive Protein Controls IL-23 Production by Human Monocytes Int J Mol Sci 2021 22
Willianne Hoepel IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming J Immunol 2020 205 3400-3407
Andrea Cortese Air pollution as a contributor to the inflammatory activity of multiple sclerosis J Neuroinflammation 2020 17 334
Payal Balraadjsing The Nature of Antibacterial Adaptive Immune Responses against Staphylococcus aureus Is Dependent on the Growth Phase and Extracellular Peptidoglycan Infect Immun 2019 88
Melissa Newling C-Reactive Protein Promotes Inflammation through FcγR-Induced Glycolytic Reprogramming of Human Macrophages J Immunol 2019 203 225-235
Willianne Hoepel FcγR-TLR Cross-Talk Enhances TNF Production by Human Monocyte-Derived DCs via IRF5-Dependent Gene Transcription and Glycolytic Reprogramming Front Immunol 2019 10 739
Serena De Matteis Immunosuppressive Treg cells acquire the phenotype of effector-T cells in chronic lymphocytic leukemia patients J Transl Med 2018 16 172
Lisa Vogelpoel FcγRIIa cross-talk with TLRs, IL-1R, and IFNγR selectively modulates cytokine production in human myeloid cells Immunobiology 2015 220 193-9