Human IL-12p70 ELISA antibody pair - 20-plate

SKU
CT750-20
Validated ELISA antibody pair with standard and conjugate; reagents available separately (1920 determinations).
Format
20-plate
Price
€ 1,055
Documentation
Data sheet
Manual
SDS
Reactivity
Human
Category
ELISA
Analyte
IL-12p70
Description
Our ELISA antibody pairs are extensively validated for high assay performance using the same reagents and materials included in U-CyTech ELISA kits. These antibody pairs are optimized to ensure reliable, sensitive, and reproducible results in a wide range of ELISA applications.
The ELISA antibody pairs are available in convenient 10- or 20-plate formats, providing 960 or 1920 determinations, respectively. Each set is supplied with either 5 or 10 vials of standards and 2 or 4 vials of Streptavidin-HRP conjugate, offering flexibility for different experimental needs and throughput requirements.
Designed for ease of use and consistent performance, these ELISA reagents support accurate quantification in immunoassays. Additional ELISA plates and reagents can be purchased separately, allowing customization of your ELISA workflow.
Description
Interleukin 12 (IL-12), also referred as IL-12p70, is a pro-inflammatory cytokine with a molecular weight of 70 kDa. It is composed of two subunits: IL-12p35 (35 kDa) and IL-12p40 (40 kDa). It plays a role in the immune response by inducing the differentiation of naive CD4 T cells into Th1 cells and activating natural killer (NK) cells. IL-12 is primarily produced by activated antigen-presenting cells (APC), including dendritic cells, macrophages, monocytes and B cells.
Alternative names
IL-12, IL12, Interleukin-12, Interleukin 12, IL-12p70, IL-12 p70, NKSF, NKSF1, CLMF, CMLF1, TCDF
Gene ID
3592, 3593

References

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Katina Schinnerling Role of dendritic cells in the pathogenesis of Whipple's disease Infect Immun 2015 83 482-91
Janine Obendorf Increased expression of CD25, CD83, and CD86, and secretion of IL-12, IL-23, and IL-10 by human dendritic cells incubated in the presence of Toll-like receptor 2 ligands and Giardia duodenalis Parasit Vectors 2013 6 317
Mario Weinhold The Attenuated Brucella abortus Strain 19 Invades, Persists in, and Activates Human Dendritic Cells, and Induces the Secretion of IL-12p70 but Not IL-23 PLoS One 2013 8 e65934
Martin Eisenblätter Nocardia farcinica activates human dendritic cells and induces secretion of interleukin-23 (IL-23) rather than IL-12p70 Infect Immun 2012 80 4195-202
Michael Fehlings Comparative analysis of the interaction of Helicobacter pylori with human dendritic cells, macrophages, and monocytes Infect Immun 2012 80 2724-34
Mohammad Rezaee Natural oils enhance IL-10 and IFN-γ production by human PBMCs cultured with Malassezia furfur Iran J Immunol 2012 9 109-19
Abhimanyu Differential serum cytokine levels are associated with cytokine gene polymorphisms in north Indians with active pulmonary tuberculosis Infect Genet Evol 2011 11 1015-22
Hua Wang Recombinant heat shock protein 65 carrying PADRE and HBV epitopes activates dendritic cells and elicits HBV-specific CTL responses Vaccine 2011 29 2328-35