Human IL-12/IL-23 p40 T cell ELISPOT kit - 2-plate
SKU
CT239-B2
All-inclusive ELISPOT kit with reagents and plates (192 determinations).
Format
2-plate
Price
€ 485
Documentation
Reactivity
Human
Category
T cell ELISPOT
Analyte
IL-12/IL-23 p40
Description
Our ELISPOT kits provide a complete, ready-to-use solution for reliable, high-performance ELISPOT assays. Each kit includes all essential components: coating and detection antibodies, streptavidin-HRP, TMB substrate, blocking stock solution, dilution buffer, Tween-20, and high-quality PVDF ELISPOT plates with lids and adhesive plate covers.
Analyte information
Description
Interleukin 12 (IL-12) is a pro-inflammatory cytokine with a molecular weight of 70 kDa, composed of two subunits: IL-12p35 (35 kDa) and IL-12p40 (40 kDa). It plays a role in the immune response by inducing the differentiation of naive CD4 T cells into Th1 cells and activating natural killer (NK) cells. IL-12 is primarily produced by activated antigen-presenting cells (APC), including dendritic cells, macrophages, monocytes and B cells.
Interleukin 23 (IL-23) promotes the expansion of Th17 cell cells. It is also heterodimeric cytokine composed of the IL-12p40 subunit and a unique p19 subunit. IL-23 is mainly secreted by macrophages and dendritic cells.
Because both IL-12 and IL-23 heterodimers share the p40 subunit, immunoassays targeting p40 will detect both cytokines.
Interleukin 23 (IL-23) promotes the expansion of Th17 cell cells. It is also heterodimeric cytokine composed of the IL-12p40 subunit and a unique p19 subunit. IL-23 is mainly secreted by macrophages and dendritic cells.
Because both IL-12 and IL-23 heterodimers share the p40 subunit, immunoassays targeting p40 will detect both cytokines.
Alternative names
IL-12, IL12, Interleukin 12, Interleukin-12, IL-12p40, IL-23, IL-12B, IL-12B, CLMF p40, NKSF, TSF
Gene ID
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