Human IL-21 T cell ELISPOT antibody pair - 10-plate
SKU
CT469-10
Validated ELISPOT antibody pair; reagents available separately (960 determinations).
Format
10-plate
Price
€ 655
Documentation
Reactivity
Human
Category
T cell ELISPOT
Analyte
IL-21
Description
Our ELISPOT antibody pairs are validated for high assay performance using the same reagents and materials included in U-CyTech ELISPOT kits. These antibody pairs are optimized for reliable and reproducible ELISPOT assays.
The antibody pairs are available in convenient 10-plate and 20-plate format, providing 960 or 1920 determinations, respectively.
Compatible reagents for ELISPOT assays can be purchased separately, allowing customization of your ELISPOT workflow.
The antibody pairs are available in convenient 10-plate and 20-plate format, providing 960 or 1920 determinations, respectively.
Compatible reagents for ELISPOT assays can be purchased separately, allowing customization of your ELISPOT workflow.
Analyte information
Description
Interleukin 21 (IL-21) is a pro-inflammatory cytokine produced by several T cell subsets, including CD4 T cells, T follicular helper (Tfh) cells, and T helper 17 (Th17) cells.
IL-21 plays a key role in T cell–dependent B cell activation within germinal centers, promoting rapid B cell proliferation and their differentiation into memory B cells and long-lived plasma cells.
In addition, IL-21 supports the proliferation, differentiation, and maintenance of CD8 T cells. It enhances the cytotoxic activity of natural killer (NK) cells and contributes to the regulation of macrophage activation.
Dysregulated or excessive production of IL-21 has been linked to several inflammatory conditions, including rheumatoid arthritis, systemic lupus erythematosus (SLE), and rejection after organ transplantation.
IL-21 plays a key role in T cell–dependent B cell activation within germinal centers, promoting rapid B cell proliferation and their differentiation into memory B cells and long-lived plasma cells.
In addition, IL-21 supports the proliferation, differentiation, and maintenance of CD8 T cells. It enhances the cytotoxic activity of natural killer (NK) cells and contributes to the regulation of macrophage activation.
Dysregulated or excessive production of IL-21 has been linked to several inflammatory conditions, including rheumatoid arthritis, systemic lupus erythematosus (SLE), and rejection after organ transplantation.
Alternative names
IL-21, Interleukin-21, IL21, Interleukin 21, Za11
Gene ID
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