Human IFN-γ T cell ELISPOT kit - 2-plate

SKU
CT230-B2
All-inclusive ELISPOT kit with reagents and plates (192 determinations).
Format
2-plate
Price
€ 485
Reactivity
Human
Category
T cell ELISPOT
Analyte
IFN-γ
Description
Our ELISPOT kits provide a complete, ready-to-use solution for reliable, high-performance ELISPOT assays. Each kit includes all essential components: coating and detection antibodies, streptavidin-HRP, TMB substrate, blocking stock solution, dilution buffer, Tween-20, and high-quality PVDF ELISPOT plates with lids and adhesive plate covers.
Description
IFN-γ is a potent immune regulating cytokine that plays a central role in activating the body’s defense against infections and malignant cells. By enhancing antigen presentation and boosting the activity of T cells and natural killer (NK) cells, IFN-γ drives strong antiviral and anti tumor responses. It is primarily produced by activated T helper 1 (Th1) cells, cytotoxic T cells, γδ T cells, NK cells, and natural killer T (NKT) cells, making it a key indicator of cellular immune activation in research and diagnostic applications.
Alternative names
IFN-γ, IFN-gamma, IFN-g, IFNg, interferon γ, interferon-γ, interferon-gamma, interferon gamma, INF-g, INF-gamma, immune interferon, Type II interferon
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References

Authors, et al. Title Journal Year Volume Pages
Stina Axelsson Long-lasting immune responses 4 years after GAD-alum treatment in children with type 1 diabetes PLoS One 2011 6 e29008
Ozlem Tapirdamaz Detailed kinetics of the direct allo-response in human liver transplant recipients: new insights from an optimized assay PLoS One 2010 5 e14452
F Vyth-Dreese Lack of anti-tumour reactivity despite enhanced numbers of circulating natural killer T cells in two patients with metastatic renal cell carcinoma Clin Exp Immunol 2010 162 447-59
S Mannering Current approaches to measuring human islet-antigen specific T cell function in type 1 diabetes Clin Exp Immunol 2010 162 197-209
Jun Liu Novel immunodominant peptide presentation strategy: a featured HLA-A*2402-restricted cytotoxic T-lymphocyte epitope stabilized by intrachain hydrogen bonds from severe acute respiratory syndrome coronavirus nucleocapsid protein J Virol 2010 84 11849-57
Georgia Afonso Critical parameters in blood processing for T-cell assays: validation on ELISpot and tetramer platforms J Immunol Methods 2010 359 28-36
L de Marquesini IFN-gamma and IL-10 islet-antigen-specific T cell responses in autoantibody-negative first-degree relatives of patients with type 1 diabetes Diabetologia 2010 53 1451-60
Fernanda Schreiber An investigation of clinical and immunological events following repeated aerodigestive tract challenge infections with live Mycobacterium bovis Bacille Calmette Guérin Vaccine 2010 28 5427-31
Mehran Gholamin Induction of cytotoxic T lymphocytes primed with tumor RNA-loaded dendritic cells in esophageal squamous cell carcinoma: preliminary step for DC vaccine design BMC Cancer 2010 10 261
James O'Beirne Generation of functional CD8+ T cells by human dendritic cells expressing glypican-3 epitopes J Exp Clin Cancer Res 2010 29 48