Human IL-12p70 T cell ELISPOT kit - 5-plate

SKU
CT240-B5
Complete ELISPOT kit including all reagents (480 determinations).
Format
5-plate
Price
€ 670
Reactivity
Human
Category
T cell ELISPOT
Analyte
IL-12p70
Description
Our ELISPOT kits provide a complete, ready-to-use solution for reliable, high-performance ELISPOT assay. Each kit includes all essential components: coating and detection antibodies, streptavidin-HRP, TMB substrate, blocking stock solution, dilution buffer, and Tween-20.
Description
Interleukin 12 (IL-12), also referred as IL-12p70, is a pro-inflammatory cytokine with a molecular weight of 70 kDa. It is composed of two subunits: IL-12p35 (35 kDa) and IL-12p40 (40 kDa). It plays a role in the immune response by inducing the differentiation of naive CD4 T cells into Th1 cells and activating natural killer (NK) cells. IL-12 is primarily produced by activated antigen-presenting cells (APC), including dendritic cells, macrophages, monocytes and B cells.
Alternative names
IL-12, IL12, Interleukin-12, Interleukin 12, IL-12p70, IL-12 p70, NKSF, NKSF1, CLMF, CMLF1, TCDF
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References

Authors, et al. Title Journal Year Volume Pages
B Brooks-Worrell Attenuation of islet-specific T cell responses is associated with C-peptide improvement in autoimmune type 2 diabetes patients Clin Exp Immunol 2013 171 164-70