Human IL-6 ELISA antibody pair - 10-plate
SKU
CT744-10
Validated ELISA antibody pair with standard and conjugate; reagents available separately (960 determinations).
Format
10-plate
Price
€ 625
Documentation
Reactivity
Human
Category
ELISA
Analyte
IL-6
Description
Our ELISA antibody pairs are extensively validated for high assay performance using the same reagents and materials included in U-CyTech ELISA kits. These antibody pairs are optimized to ensure reliable, sensitive, and reproducible results in a wide range of ELISA applications.
The ELISA antibody pairs are available in convenient 10- or 20-plate formats, providing 960 or 1920 determinations, respectively. Each set is supplied with either 5 or 10 vials of standards and 2 or 4 vials of Streptavidin-HRP conjugate, offering flexibility for different experimental needs and throughput requirements.
Designed for ease of use and consistent performance, these ELISA reagents support accurate quantification in immunoassays. Additional ELISA plates and reagents can be purchased separately, allowing customization of your ELISA workflow.
The ELISA antibody pairs are available in convenient 10- or 20-plate formats, providing 960 or 1920 determinations, respectively. Each set is supplied with either 5 or 10 vials of standards and 2 or 4 vials of Streptavidin-HRP conjugate, offering flexibility for different experimental needs and throughput requirements.
Designed for ease of use and consistent performance, these ELISA reagents support accurate quantification in immunoassays. Additional ELISA plates and reagents can be purchased separately, allowing customization of your ELISA workflow.
Analyte information
Description
Interleukin-6 (IL-6) is a multifunctional cytokine produced by a wide range of cells. These include innate immune cells as macrophages, dendritic cells, and mast cells, as well as B cells, and certain CD4 effector T helper (Th) cells. In addition, non-leukocyte cells such as endothelial cells, fibroblasts, astrocytes, epithelial cells can also produce IL-6.
Although IL-6 is well known for its strong pro-inflammatory effects, it also plays an important role in regulating adaptive immunity. Specifically, IL-6 influences the balance between different T helper cell subsets. It promotes the differentiation of Th2 cells by increasing the production of IL-4 and IL-13, while simultaneously reducing IFN-γ, which is typically associated with Th1 responses. Furthermore, IL-6 contributes to the differentiation of Th17 cells when acting in combination with TGF-β. At the same time, IL-6 can inhibit the activity of regulatory T (Treg) cells in vitro. Since TGF-β alone promotes Treg cell development, the presence of IL-6 is thought to shift the balance toward Th17 cell differentiation. In this way, IL-6 plays a key role in fine-tuning the equilibrium between pro-inflammatory Th17 cells and immunosuppressive Treg cells.
Although IL-6 is well known for its strong pro-inflammatory effects, it also plays an important role in regulating adaptive immunity. Specifically, IL-6 influences the balance between different T helper cell subsets. It promotes the differentiation of Th2 cells by increasing the production of IL-4 and IL-13, while simultaneously reducing IFN-γ, which is typically associated with Th1 responses. Furthermore, IL-6 contributes to the differentiation of Th17 cells when acting in combination with TGF-β. At the same time, IL-6 can inhibit the activity of regulatory T (Treg) cells in vitro. Since TGF-β alone promotes Treg cell development, the presence of IL-6 is thought to shift the balance toward Th17 cell differentiation. In this way, IL-6 plays a key role in fine-tuning the equilibrium between pro-inflammatory Th17 cells and immunosuppressive Treg cells.
Alternative names
IL-6, Interleukin 6, interleukin-6, IL6, IFN-beta 2, IFNB2, BSF-2, BSF2, HGF, HSF, CDF, BSF-2
Gene ID
Image
