mAb anti-mouse IL-2 (clone JES6-1A12) - 0.5 mg

SKU

CT335

Rat monoclonal anti-mouse IL-2 (IgG2a, κ)

Format

0.5 mg

Price

€ 315

Documentation

Data sheet

SDS

Reactivity

Mouse

Category

Antibodies

Analyte

IL-2

Description

The monoclonal anti-mouse IL-2 antibody recognizes both natural and recombinant mouse IL-2. The antibody is suitable for ELISA, neutralization assays, intracellular staining and immunoprecipitation.

Analyte information

Description

Interleukin-2 (IL-2) is a key cytokine produced by activated T cells that regulates immune responses. It drives the proliferation and differentiation of helper, cytotoxic, and regulatory T cells, while enhancing natural killer (NK) cell activity. IL-2 plays a central role in balancing immune activation and tolerance, making it essential for effective defense against infections.

Alternative names

IL-2, Interleukin 2, Interleukin-2, IL2, TCGF, T cell growth factor, lymphokine

Gene ID

16183

References

Authors, et al.	Title	Journal	Year	Volume	Pages
R Gorczynski	An immunoadhesin incorporating the molecule OX-2 is a potent immunosuppressant that prolongs allo- and xenograft survival	J Immunol	1999	163	1654-60
R Carson	Simultaneous quantitation of 15 cytokines using a multiplexed flow cytometric assay	J Immunol Methods	1999	227	41-52
M Assenmacher	Commitment of individual Th1-like lymphocytes to expression of IFN-gamma versus IL-4 and IL-10: selective induction of IL-10 by sequential stimulation of naive Th cells with IL-12 and IL-4	J Immunol	1998	161	2825-32
M Assenmacher	Sequential production of IL-2, IFN-gamma and IL-10 by individual staphylococcal enterotoxin B-activated T helper lymphocytes	Eur J Immunol	1998	28	1534-43
U Grohmann	A tumor-associated and self antigen peptide presented by dendritic cells may induce T cell anergy in vivo, but IL-12 can prevent or revert the anergic state	J Immunol	1997	158	3593-602