Monkey IL-10 ELISA kit - 5-plate

SKU
CT146A
All-inclusive ELISA kit with reagents and plates (480 determinations).
Species reactivity: rhesus macaque, cynomolgus monkey, pig-tailed macaque, baboon, African green monkey.
Format
5-plate
Price
€ 530
Reactivity
Monkey
Category
ELISA
Analyte
IL-10
Range
2-128 pg/ml
Description
Our sandwich ELISA kits are developed for the determination of cytokines in culture supernatant, serum and plasma. Each kit includes all reagents required to perform up to 480 ELISA determinations: coating and detection antibodies, standards, streptavidin-HRP conjugate, TMB substrate, stop solution, cytokine stabilization buffer, BSA stock solution, ELISA plates and adhesive plate covers.
Description
Interleukin 10 (IL-10) is an anti-inflammatory cytokine belonging to the class-2 cytokine family. It plays a crucial role in regulating immune responses and controlling inflammation. IL-10 suppresses production of pro-inflammatory cytokines, including IL-1, IL-6, IL-8, IL-12, IFN-γ and TNF-α.
IL-10 is primarily produced by activated T cell, especially Th2 cells, but is also secreted by B cells, monocytes and macrophages.
Alternative names
IL-10, IL10, Interleukin-10, Interleukin 10, IL10A, IL-10A, CSIF, Cytokine synthesis inhibitory factor, TGIF, T cell growth inhibitory factor
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References

Authors, et al. Title Journal Year Volume Pages
Jonas Klingström Passive immunization protects cynomolgus macaques against Puumala hantavirus challenge Antivir Ther 2008 13 125-33
C Asiedu Cloning and characterization of recombinant rhesus macaque IL-10/Fc(ala-ala) fusion protein: a potential adjunct for tolerance induction strategies Cytokine 2007 40 183-92
Chang Wang Site-specific UBITh amyloid-beta vaccine for immunotherapy of Alzheimer's disease Vaccine 2007 25 3041-52
Lorenzo Mortara Phenotype and function of myeloid dendritic cells derived from African green monkey blood monocytes J Immunol Methods 2006 308 138-55
Christopher Kornfeld Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS J Clin Invest 2005 115 1082-91
Koen Van Rompay Tenofovir primes rhesus macaque cells in vitro for enhanced interleukin-12 secretion Antiviral Res 2004 63 133-8
Rik De Swart Immunization of macaques with formalin-inactivated respiratory syncytial virus (RSV) induces interleukin-13-associated hypersensitivity to subsequent RSV infection J Virol 2002 76 11561-9
Davorka Messmer Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells J Immunol 2002 169 4172-82
Erin Mehlhop Enhanced in vitro stimulation of rhesus macaque dendritic cells for activation of SIV-specific T cell responses J Immunol Methods 2002 260 219-34
N Polakos Characterization of hepatitis C virus core-specific immune responses primed in rhesus macaques by a nonclassical ISCOM vaccine J Immunol 2001 166 3589-98