mAb anti-rat IFN-γ (clone DB-1) - 0.5 mg

SKU
CT032
Mouse monoclonal anti-rat IFN-γ antibody (IgG1, κ).
For bulk pricing and availability, contact cs@ucytech.com.
Format
0.5 mg
Price
€ 340
Documentation
Reactivity
Rat
Category
Antibodies
Analyte
IFN-γ
Description
Clone DB-1 is a highly specific mouse monoclonal antibody against rat IFN-γ (IgG1, κ). DB-1 was capable of complete binding of both natural and recombinant rat and mouse IFN-γ. The antibody shows no cross-reactivity with IFN-α and IFN-β, or human interferons.
DB-1 is ideal for ELISA, ELISPOT, immunohistochemistry (frozen tissue) and intracellular staining.
Description
IFN-γ is a potent immune regulating cytokine that plays a central role in activating the body’s defense against infections and malignant cells. By enhancing antigen presentation and boosting the activity of T cells and natural killer (NK) cells, IFN-γ drives strong antiviral and anti tumor responses. It is primarily produced by activated T helper 1 (Th1) cells, cytotoxic T cells, γδ T cells, NK cells, and natural killer T (NKT) cells, making it a key indicator of cellular immune activation in research and diagnostic applications.
Alternative names
DB-1, DB1
IFN-γ, IFN-gamma, IFN-g, IFNg, interferon γ, interferon-γ, interferon-gamma, interferon gamma, INF-g, INF-gamma, immune interferon, Type II interferon
Image
CT101

References

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P van der Meide Discontinuation of treatment with IFN-beta leads to exacerbation of experimental autoimmune encephalomyelitis in Lewis rats. Rapid reversal of the antiproliferative activity of IFN-beta and excessive expansion of autoreactive T cells as disease promoting mechanisms J Neuroimmunol 1998 84 14-23