Human IL-13 T cell ELISPOT kit - 5-plate

SKU
CT236-B5
Complete ELISPOT kit including all reagents (480 determinations).
Format
5-plate
Price
€ 670
Documentation
Data sheet
Manual
SDS
Reactivity
Human
Category
T cell ELISPOT
Analyte
IL-13
Description
Our ELISPOT kits provide a complete, ready-to-use solution for reliable, high-performance ELISPOT assay. Each kit includes all essential components: coating and detection antibodies, streptavidin-HRP, TMB substrate, blocking stock solution, dilution buffer, and Tween-20.
Description
Interleukin 13 (IL-13) is a cytokine primarily produced by activated T helper (Th2) cells. It plays an important role in B-cell maturation and differentiation. In addition, IL-13 downregulates macrophage activity and inhibits the production of pro-inflammatory cytokines and chemokines.
Although Th2 cells are the main source, IL-13 is also produced by other immune cell, including natural killer (NK) cells, mast cells, basophils and eosinophils. These cells contribute to its role in allergic responses.
Alternative names
IL-13, Interleukin-13, IL13, Interleukin 13, NC30, P600
Gene ID
3596
Related Products
CT236-B2 - Human IL-13 T cell ELISPOT kit - 2-plate

References

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Marieke Griffioen Analysis of T-cell responses in metastatic melanoma patients vaccinated with dendritic cells pulsed with tumor lysates Cancer Immunol Immunother 2004 53 715-22
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Nanette Schloot Comparison of cytokine ELISpot assay formats for the detection of islet antigen autoreactive T cells. Report of the third immunology of diabetes society T-cell workshop J Autoimmun 2003 21 365-76
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I Raz Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial Lancet 2001 358 1749-53
S Martin Development of type 1 diabetes despite severe hereditary B-cell deficiency N Engl J Med 2001 345 1036-40