Human IL-23 ELISA antibody pair - 10-plate

SKU
CT567-10
Validated ELISA antibody pair with standard and conjugate; reagents available separately (960 determinations).
Format
10-plate
Price
€ 625
Documentation
Data sheet
Manual
SDS
Reactivity
Human
Category
ELISA
Analyte
IL-23
Description
Our ELISA antibody pairs are extensively validated for high assay performance using the same reagents and materials included in U-CyTech ELISA kits. These antibody pairs are optimized to ensure reliable, sensitive, and reproducible results in a wide range of ELISA applications.
The ELISA antibody pairs are available in convenient 10- or 20-plate formats, providing 960 or 1920 determinations, respectively. Each set is supplied with either 5 or 10 vials of standards and 2 or 4 vials of Streptavidin-HRP conjugate, offering flexibility for different experimental needs and throughput requirements.
Designed for ease of use and consistent performance, these ELISA reagents support accurate quantification in immunoassays. Additional ELISA plates and reagents can be purchased separately, allowing customization of your ELISA workflow.
Description
Interleukin-23 (IL-23) is a pro-inflammatory cytokine that plays a critical role in immune regulation. IL-23 is a heterodimer composed of two subunits: IL12p40 and IL-23p19. It is primarily secreted by antigen-presenting cells, including dendritic cell, macrophages and monocytes.
IL-23 is responsible for the expansion and maintenance of T helper 17 (Th17) cells, a subset of CD4 T cells involved in host defense and inflammatory responses.
Alternative names
IL-23, Interleukine-23, IL23, Interleukin 23, IL23A, IL-23p19, P19,
Gene ID
51561, 3593

References

Authors, et al. Title Journal Year Volume Pages
Lynn Mes IgA2 immune complexes selectively promote inflammation by human CD103+ dendritic cells Front Immunol 2023 14 1116435
Florianne Hafkamp Vitamin D3 Priming of Dendritic Cells Shifts Human Neutrophil-Dependent Th17 Cell Development to Regulatory T Cells Front Immunol 2022 13 872665
Chiara Geyer C-Reactive Protein Controls IL-23 Production by Human Monocytes Int J Mol Sci 2021 22
Willianne Hoepel IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming J Immunol 2020 205 3400-3407
Andrea Cortese Air pollution as a contributor to the inflammatory activity of multiple sclerosis J Neuroinflammation 2020 17 334
Payal Balraadjsing The Nature of Antibacterial Adaptive Immune Responses against Staphylococcus aureus Is Dependent on the Growth Phase and Extracellular Peptidoglycan Infect Immun 2019 88
Melissa Newling C-Reactive Protein Promotes Inflammation through FcγR-Induced Glycolytic Reprogramming of Human Macrophages J Immunol 2019 203 225-235
Serena De Matteis Immunosuppressive Treg cells acquire the phenotype of effector-T cells in chronic lymphocytic leukemia patients J Transl Med 2018 16 172
Lisa Vogelpoel FcγRIIa cross-talk with TLRs, IL-1R, and IFNγR selectively modulates cytokine production in human myeloid cells Immunobiology 2015 220 193-9
Lisa Vogelpoel Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages Nat Commun 2014 5 5444